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Crystallization and preliminary X-ray analysis of the N-terminal domain of human thioredoxin-interacting protein

Thioredoxin-interacting protein (TXNIP) is a negative regulator of thioredoxin and its roles in the pathologies of diabetes and cardiovascular diseases have marked it out as a potential drug target. Expression of TXNIP is robustly induced under various stress conditions such as high glucose, heat sh...

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Autori principali: Polekhina, Galina, Ascher, David Benjamin, Kok, Shie Foong, Waltham, Mark
Natura: Artigo
Lingua:Inglês
Pubblicazione: International Union of Crystallography 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3087653/
https://ncbi.nlm.nih.gov/pubmed/21543874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309111010347
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