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Longitudinal modeling of frontal cognition in APOE ε4 homozygotes, heterozygotes, and noncarriers

BACKGROUND: Fibrillar amyloid deposition preferentially affects the frontal lobes, temporal pole/neocortex, and posterior cingulate by age 65 years in APOE ε4 carriers prior to the diagnosis of mild cognitive impairment (MCI) and Alzheimer disease (AD), but is it impairing frontally mediated neurops...

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書誌詳細
主要な著者: Caselli, R.J., Dueck, A.C., Locke, D.E.C., Hoffman-Snyder, C.R., Woodruff, B.K., Rapcsak, S.Z., Reiman, E.M.
フォーマット: Artigo
言語:Inglês
出版事項: Lippincott Williams & Wilkins 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3087407/
https://ncbi.nlm.nih.gov/pubmed/21502596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0b013e3182167147
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