Longitudinal modeling of frontal cognition in APOE ε4 homozygotes, heterozygotes, and noncarriers

BACKGROUND: Fibrillar amyloid deposition preferentially affects the frontal lobes, temporal pole/neocortex, and posterior cingulate by age 65 years in APOE ε4 carriers prior to the diagnosis of mild cognitive impairment (MCI) and Alzheimer disease (AD), but is it impairing frontally mediated neurops...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Caselli, R.J., Dueck, A.C., Locke, D.E.C., Hoffman-Snyder, C.R., Woodruff, B.K., Rapcsak, S.Z., Reiman, E.M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Lippincott Williams & Wilkins 2011
Pynciau:
Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3087407/
https://ncbi.nlm.nih.gov/pubmed/21502596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0b013e3182167147
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