Longitudinal modeling of frontal cognition in APOE ε4 homozygotes, heterozygotes, and noncarriers

BACKGROUND: Fibrillar amyloid deposition preferentially affects the frontal lobes, temporal pole/neocortex, and posterior cingulate by age 65 years in APOE ε4 carriers prior to the diagnosis of mild cognitive impairment (MCI) and Alzheimer disease (AD), but is it impairing frontally mediated neurops...

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Autors principals: Caselli, R.J., Dueck, A.C., Locke, D.E.C., Hoffman-Snyder, C.R., Woodruff, B.K., Rapcsak, S.Z., Reiman, E.M.
Format: Artigo
Idioma:Inglês
Publicat: Lippincott Williams & Wilkins 2011
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3087407/
https://ncbi.nlm.nih.gov/pubmed/21502596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0b013e3182167147
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