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Gene–Environment Interactions in Parkinson's Disease: The Importance of Animal Modeling

Parkinson's disease (PD), a late-onset neurodegenerative disorder, occurs most commonly in a “sporadic” (idiopathic) form, without a clearly defined genetic basis and only a vaguely delineated pathogenesis. Together, the various monogenic forms of PD (i.e., those arising from mutations in singl...

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Détails bibliographiques
Auteurs principaux: Horowitz, MP, Greenamyre, JT
Format: Artigo
Langue:Inglês
Publié: 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3085510/
https://ncbi.nlm.nih.gov/pubmed/20811350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/clpt.2010.138
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