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Efficient generation of transgene-free induced pluripotent stem cells from normal and neoplastic bone marrow and cord blood mononuclear cells

Reprogramming blood cells to induced pluripotent stem cells (iPSCs) provides a novel tool for modeling blood diseases in vitro. However, the well-known limitations of current reprogramming technologies include low efficiency, slow kinetics, and transgene integration and residual expression. In the p...

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Bibliografske podrobnosti
Main Authors: Hu, Kejin, Yu, Junying, Suknuntha, Kran, Tian, Shulan, Montgomery, Karen, Choi, Kyung-Dal, Stewart, Ron, Thomson, James A., Slukvin, Igor I.
Format: Artigo
Jezik:Inglês
Izdano: American Society of Hematology 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3083304/
https://ncbi.nlm.nih.gov/pubmed/21296996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-07-298331
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