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Substance-specific and shared transcription and epigenetic changes in the human hippocampus chronically exposed to cocaine and alcohol

The hippocampus is a key brain region involved in both short- and long-term memory processes and may play critical roles in drug-associated learning and addiction. Using whole genome sequencing of mRNA transcripts (RNA-Seq) and immunoprecipitation-enriched genomic DNA (ChIP-Seq) coupled with histone...

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Detalhes bibliográficos
Main Authors: Zhou, Zhifeng, Yuan, Qiaoping, Mash, Deborah C., Goldman, David
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3081016/
https://ncbi.nlm.nih.gov/pubmed/21464311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1018514108
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