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Trefoil factor 1 acts to suppress senescence induced by oncogene activation during the cellular transformation process
Senescence is a cellular stress response characterized by persistent cell growth arrest under various stress conditions, including oncogene activation or tumor suppressor loss, which functions as a critical barrier that must be overcome to allow the progression from a precancerous or preinvasive les...
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Main Authors: | , , , , , |
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Format: | Artigo |
Language: | Inglês |
Published: |
National Academy of Sciences
2011
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Subjects: | |
Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3081012/ https://ncbi.nlm.nih.gov/pubmed/21451135 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1017269108 |
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