Usher type 1G protein sans is a critical component of the tip-link complex, a structure controlling actin polymerization in stereocilia

The mechanotransducer channels of auditory hair cells are gated by tip-links, oblique filaments that interconnect the stereocilia of the hair bundle. Tip-links stretch from the tips of stereocilia in the short and middle rows to the sides of neighboring, taller stereocilia. They are made of cadherin...

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Autori principali: Caberlotto, Elisa, Michel, Vincent, Foucher, Isabelle, Bahloul, Amel, Goodyear, Richard J., Pepermans, Elise, Michalski, Nicolas, Perfettini, Isabelle, Alegria-Prévot, Olinda, Chardenoux, Sébastien, Do Cruzeiro, Marcio, Hardelin, Jean-Pierre, Richardson, Guy P., Avan, Paul, Weil, Dominique, Petit, Christine
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2011
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3078398/
https://ncbi.nlm.nih.gov/pubmed/21436032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1017114108
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