Decreased Numbers of Blood Dendritic Cells and Defective Function of Regulatory T Cells in Antineutrophil Cytoplasmic Antibody-Associated Vasculitis

BACKGROUND: Dendritic cells (DC) and regulatory cells (Treg) play pivotal roles in controlling both normal and autoimmune adaptive immune responses. DC are the main antigen-presenting cells to T cells, and they also control Treg functions. In this study, we examined the frequency and phenotype of DC...

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Main Authors: Rimbert, Marie, Hamidou, Mohamed, Braudeau, Cécile, Puéchal, Xavier, Teixeira, Luis, Caillon, Hélène, Néel, Antoine, Audrain, Marie, Guillevin, Loic, Josien, Régis
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2011
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3073002/
https://ncbi.nlm.nih.gov/pubmed/21494636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0018734
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