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Genetic deficiency of aldose reductase counteracts the development of diabetic nephropathy in C57BL/6 mice
AIMS/HYPOTHESIS: The aim of the study was to investigate the effects of genetic deficiency of aldose reductase in mice on the development of key endpoints of diabetic nephropathy. METHODS: A line of Ar (also known as Akr1b3)-knockout (KO) mice, a line of Ar-bitransgenic mice and control C57BL/6 mice...
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| Hauptverfasser: | , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Springer-Verlag
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3071933/ https://ncbi.nlm.nih.gov/pubmed/21267539 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-011-2045-4 |
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