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TRANSIENT KINETIC ANALYSIS OF L-SERINE INTERACTION WITH E. COLI D-3-PHOSPHOGLYCERATE DEHYDROGENASE CONTAINING AMINO ACID MUTATIONS IN THE HINGE REGIONS
In E. coli D-3-phosphoglycerate dehydrogenase, the amino acid sequences G294–G295 and G336–G337 are found between structural domains and appear to function as hinge regions. Mutagenesis studies of these sequences showed that bulky side chains had significant effects on the kinetic properties of the...
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| Main Author: | |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2011
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3071459/ https://ncbi.nlm.nih.gov/pubmed/21391703 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi200211z |
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