Evolution combined with genomic study elucidates genetic bases of isobutanol tolerance in Escherichia coli

BACKGROUND: Isobutanol is a promising next-generation biofuel with demonstrated high yield microbial production, but the toxicity of this molecule reduces fermentation volumetric productivity and final titer. Organic solvent tolerance is a complex, multigenic phenotype that has been recalcitrant to...

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Autori principali: Minty, Jeremy J, Lesnefsky, Ann A, Lin, Fengming, Chen, Yu, Zaroff, Ted A, Veloso, Artur B, Xie, Bin, McConnell, Catie A, Ward, Rebecca J, Schwartz, Donald R, Rouillard, Jean-Marie, Gao, Yuan, Gulari, Erdogan, Lin, Xiaoxia Nina
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2011
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3071312/
https://ncbi.nlm.nih.gov/pubmed/21435272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2859-10-18
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