Impaired Virulence and In Vivo Fitness of Colistin-Resistant Acinetobacter baumannii

Acinetobacter baumannii (American Type Culture Collection strain 19606) acquires mutations in the pmrB gene during the in vitro development of resistance to colistin. The colistin-resistant strain has lower affinity for colistin, reduced in vivo fitness (competition index, .016), and decreased virul...

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Bibliographic Details
Main Authors: López-Rojas, Rafael, Domínguez-Herrera, Juan, McConnell, Michael J., Docobo-Peréz, Fernando, Smani, Younes, Fernández-Reyes, María, Rivas, Luis, Pachón, Jerónimo
Format: Artigo
Language:Inglês
Published: Oxford University Press 2011
Subjects:
Major Articles and Brief Reports
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3071218/
https://ncbi.nlm.nih.gov/pubmed/21216865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiq086
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