Sensitization of Cells Overexpressing Multidrug Resistant Proteins by Pluronic P85

PURPOSE: This study evaluated the chemosensitizing effects of Pluronic P85 (P85) on the cells expressing multidrug resistance-associated proteins, MRP1 and MRP2. METHODS: Cell models included MRP1- and MRP2-transfected MDCKII cells, as well as doxorubicin-selected COR-L23/R cells overexpressing MRP1...

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Autores principales: Batrakova, Elena V., Li, Shu, Alakhov, Valery Yu., Elmquist, William F., Miller, Donald W., Kabanov, Alexander V.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2003
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3070744/
https://ncbi.nlm.nih.gov/pubmed/14620511
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