Epidermal Growth Factor Receptor-targeted (131)I-therapy of Liver Cancer Following Systemic Delivery of the Sodium Iodide Symporter Gene

We recently demonstrated tumor-selective iodide uptake and therapeutic efficacy of radioiodine in neuroblastoma tumors after systemic nonviral polyplex-mediated sodium iodide symporter (NIS) gene delivery. In the present study, we used novel polyplexes based on linear polyethylenimine (LPEI), polyet...

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Detalhes bibliográficos
Main Authors: Klutz, Kathrin, Schaffert, David, Willhauck, Michael J, Grünwald, Geoffrey K, Haase, Rudolf, Wunderlich, Nathalie, Zach, Christian, Gildehaus, Franz J, Senekowitsch-Schmidtke, Reingard, Göke, Burkhard, Wagner, Ernst, Ogris, Manfred, Spitzweg, Christine
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3070097/
https://ncbi.nlm.nih.gov/pubmed/21245850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2010.296
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