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Embryonic Senescence and Laminopathies in a Progeroid Zebrafish Model

BACKGROUND: Mutations that disrupt the conversion of prelamin A to mature lamin A cause the rare genetic disorder Hutchinson-Gilford progeria syndrome and a group of laminopathies. Our understanding of how A-type lamins function in vivo during early vertebrate development through aging remains limit...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Koshimizu, Eriko, Imamura, Shintaro, Qi, Jie, Toure, Jamal, Valdez, Delgado M., Carr, Christopher E., Hanai, Jun-ichi, Kishi, Shuji
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2011
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3068137/
https://ncbi.nlm.nih.gov/pubmed/21479207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0017688
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