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Embryonic Senescence and Laminopathies in a Progeroid Zebrafish Model
BACKGROUND: Mutations that disrupt the conversion of prelamin A to mature lamin A cause the rare genetic disorder Hutchinson-Gilford progeria syndrome and a group of laminopathies. Our understanding of how A-type lamins function in vivo during early vertebrate development through aging remains limit...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3068137/ https://ncbi.nlm.nih.gov/pubmed/21479207 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0017688 |
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