MUC1 enhances invasiveness of pancreatic cancer cells by inducing epithelial to mesenchymal transition

Increased motility and invasiveness of pancreatic cancer cells are associated with epithelial to mesenchymal transition (EMT). Snai1 and Slug are zinc-finger transcription factors that trigger this process by repressing E-cadherin and enhancing vimentin and N-Cadherin protein expression. However, th...

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Hlavní autoři: Roy, Lopamudra Das, Sahraei, Mahnaz, Subramani, Durai B., Besmer, Dahlia, Nath, Sritama, Tinder, Teresa L., Bajaj, Ekta, Shanmugam, Kandavel, Lee, Yong Yook, Hwang, Sun IL, Gendler, Sandra J., Mukherjee, Pinku
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3063863/
https://ncbi.nlm.nih.gov/pubmed/21102519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2010.526
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