An association between a common variant (G972R) in the IRS-1 gene and sex hormone levels in postmenopausal breast cancer survivors

Insulin receptor substrate-1 (IRS-1) is a key downstream signaling molecule common to both the insulin and IGF signaling pathways that can interact with the estrogen pathway to regulate breast cell growth. We investigated whether a putative functional variant for IRS-1 (G972R) influences circulating...

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Main Authors: Fan, Jing, McKean-Cowdin, Roberta, Bernstein, Leslie, Stanczyk, Frank Z., Li, Arthur Xuejun, Ballard-Barbash, Rachel, McTiernan, Anne, Baumgartner, Richard, Gilliland, Frank
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2006
Ábhair:
Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3063148/
https://ncbi.nlm.nih.gov/pubmed/16752222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-006-9211-2
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