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An association between a common variant (G972R) in the IRS-1 gene and sex hormone levels in postmenopausal breast cancer survivors

Insulin receptor substrate-1 (IRS-1) is a key downstream signaling molecule common to both the insulin and IGF signaling pathways that can interact with the estrogen pathway to regulate breast cell growth. We investigated whether a putative functional variant for IRS-1 (G972R) influences circulating...

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Detalhes bibliográficos
Main Authors: Fan, Jing, McKean-Cowdin, Roberta, Bernstein, Leslie, Stanczyk, Frank Z., Li, Arthur Xuejun, Ballard-Barbash, Rachel, McTiernan, Anne, Baumgartner, Richard, Gilliland, Frank
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3063148/
https://ncbi.nlm.nih.gov/pubmed/16752222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-006-9211-2
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