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Increased Sensitivity of Estrogen Receptor Alpha Overexpressing Antral Follicles to Methoxychlor and Its Metabolites

Methoxychlor (MXC), an organochlorine pesticide, and its metabolites, mono-hydroxy MXC (MOH) and bis-hydroxy MXC (HPTE) are known ovarian toxicants and can cause inhibition of antral follicle growth. Since these chemicals bind to estrogen receptor alpha (ESR1), we hypothesized that ovaries overexpre...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Paulose, Tessie, Hernández-Ochoa, Isabel, Basavarajappa, Mallikarjuna S., Peretz, Jackye, Flaws, Jodi A.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Oxford University Press 2011
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3061483/
https://ncbi.nlm.nih.gov/pubmed/21252393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfr011
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