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Increased Sensitivity of Estrogen Receptor Alpha Overexpressing Antral Follicles to Methoxychlor and Its Metabolites

Methoxychlor (MXC), an organochlorine pesticide, and its metabolites, mono-hydroxy MXC (MOH) and bis-hydroxy MXC (HPTE) are known ovarian toxicants and can cause inhibition of antral follicle growth. Since these chemicals bind to estrogen receptor alpha (ESR1), we hypothesized that ovaries overexpre...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Paulose, Tessie, Hernández-Ochoa, Isabel, Basavarajappa, Mallikarjuna S., Peretz, Jackye, Flaws, Jodi A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2011
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3061483/
https://ncbi.nlm.nih.gov/pubmed/21252393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfr011
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