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p21(CIP-1/WAF-1) Induction Is Required to Inhibit Prostate Cancer Growth Elicited by Deficient Expression of the Wnt Inhibitor Dickkopf-1 (DKK-1)
Osteoblastic bone metastases are the most common metastases produced by human prostate cancers (PCa). Deregulated activity of WNT growth factors resulting from overexpression of the WNT inhibitor DKK-1 is known to contribute to formation of the osteoblastic component of PCa skeletal bone metastases....
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3059079/ https://ncbi.nlm.nih.gov/pubmed/21098705 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-0440 |
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