Acid sphingomyelinase regulates glucose and lipid metabolism in hepatocytes through AKT activation and AMP-activated protein kinase suppression

Acid sphingomyelinase (ASM) regulates the homeostasis of sphingolipids, including ceramides and sphingosine-1-phosphate (S1P). Because sphingolipids regulate AKT activation, we investigated the role of ASM in hepatic glucose and lipid metabolism. Initially, we overexpressed ASM in the livers of wild...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Osawa, Yosuke, Seki, Ekihiro, Kodama, Yuzo, Suetsugu, Atsushi, Miura, Kouichi, Adachi, Masayuki, Ito, Hiroyasu, Shiratori, Yoshimune, Banno, Yoshiko, Olefsky, Jerrold M., Nagaki, Masahito, Moriwaki, Hisataka, Brenner, David A., Seishima, Mitsuru
Format: Artigo
Sprog:Inglês
Udgivet: Federation of American Societies for Experimental Biology 2011
Fag:
Research Communications
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3058702/
https://ncbi.nlm.nih.gov/pubmed/21163859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.10-168351
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker