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Chromatin unfolding by Cdt1 regulates MCM loading via opposing functions of HBO1 and HDAC11-geminin

The efficiency of metazoan origins of DNA replication is known to be enhanced by histone acetylation near origins. Although this correlates with increased MCM recruitment, the mechanism by which such acetylation regulates MCM loading is unknown. We show here that Cdt1 induces large-scale chromatin d...

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מידע ביבליוגרפי
Main Authors: Wong, Philip G, Glozak, Michele A, Cao, Thinh V, Vaziri, Cyrus, Seto, Edward, Alexandrow, Mark G
פורמט: Artigo
שפה:Inglês
יצא לאור: Landes Bioscience 2010
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3055186/
https://ncbi.nlm.nih.gov/pubmed/20980834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.9.21.13596
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