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Ataxia telangiectasia mutated influences cytochrome c oxidase activity

Cells lacking ataxia telangiectasia mutated (ATM) have impaired mitochondrial function. Furthermore, mammalian cells lacking ATM have increased levels of reactive oxygen species (ROS) as well as mitochondrial DNA (mtDNA) deletions in the region encoding for cytochrome c oxidase (COX). We hypothesize...

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Detalhes bibliográficos
Main Authors: Patel, Akshar Y., McDonald, Todd M., Spears, Larry D., Ching, James Kain, Fisher, Jonathan S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3055168/
https://ncbi.nlm.nih.gov/pubmed/21266166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2011.01.075
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