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Cytoplasmic Skp2 Expression Is Increased in Human Melanoma and Correlated with Patient Survival
BACKGROUND: S-phase kinase protein 2 (Skp2), an F-box protein, targets cell cycle regulators via ubiquitin-mediated degradation. Skp2 is frequently overexpressed in a variety of cancers and associated with patient survival. In melanoma, however, the prognostic significance of subcellular Skp2 expres...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
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Public Library of Science
2011
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3046256/ https://ncbi.nlm.nih.gov/pubmed/21386910 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0017578 |
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