Phosphodiesterase 4 inhibition attenuates atrial natriuretic peptide-induced vascular hyperpermeability and loss of plasma volume

Inhibition of phosphodiesterase 4 (PDE4) to increase endothelial cAMP and stabilize the endothelial barrier attenuates acute inflammatory increases in vascular permeability. We extended this approach to attenuate physiological increases in vascular permeability in response to atrial natriuretic pept...

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Hlavní autoři: Lin, Yueh-Chen, Samardzic, Haris, Adamson, Roger H, Renkin, Eugene M, Clark, Joyce F, Reed, Rolf K, Curry, Fitz-Roy E
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Science Inc 2011
Témata:
Cardiovascular
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3043537/
https://ncbi.nlm.nih.gov/pubmed/21098005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2010.199588
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