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Wt1 controls retinoic acid signalling in embryonic epicardium through transcriptional activation of Raldh2
Epicardial-derived signals are key regulators of cardiac embryonic development. An important part of these signals is known to relate to a retinoic acid (RA) receptor-dependent mechanism. RA is a potent morphogen synthesised by Raldh enzymes, Raldh2 being the predominant one in mesodermal tissues. D...
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| Главные авторы: | , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Company of Biologists
2011
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3042868/ https://ncbi.nlm.nih.gov/pubmed/21343363 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.044594 |
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