Impaired neoangiogenesis in β(2)–adrenoceptor gene-deficient mice: restoration by intravascular human β(2)–adrenoceptor gene transfer and role of NFκB and CREB transcription factors

BACKGROUND AND PURPOSE: There is much evidence supporting the role of β(2)-adrenoceptors (β(2)AR) in angiogenesis but the mechanisms underlying their effects have not been elucidated. Hence, we studied post-ischaemic angiogenesis in the hindlimb (HL) of β(2)AR knock-out mice (β(2)AR−/−) in vivo and...

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Détails bibliographiques
Auteurs principaux: Ciccarelli, Michele, Sorriento, Daniela, Cipolletta, Ersilia, Santulli, Gaetano, Fusco, Anna, Zhou, Rui-Hai, Eckhart, Andrea D, Peppel, Karsten, Koch, Walter J, Trimarco, Bruno, Iaccarino, Guido
Format: Artigo
Langue:Inglês
Publié: Blackwell Publishing Ltd 2011
Sujets:
Research Papers
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3041259/
https://ncbi.nlm.nih.gov/pubmed/20958287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2010.01078.x
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