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Leptin pro-angiogenic signature in breast cancer is linked to IL-1 signalling
BACKGROUND: Leptin and interleukin-1 (IL-1) upregulate vascular endothelial growth factor (VEGF), promote angiogenesis and are related to worse prognosis of breast cancer. However, it is unknown whether leptin regulates IL-1, and whether these effects are related to leptin-induction of VEGF/VEGFR2 i...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3039812/ https://ncbi.nlm.nih.gov/pubmed/21139583 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6606013 |
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