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RNAi-Mediated Knock-Down of Arylamine N-acetyltransferase-1 Expression Induces E-cadherin Up-Regulation and Cell-Cell Contact Growth Inhibition

Arylamine N-acetyltransferase-1 (NAT1) is an enzyme that catalyzes the biotransformation of arylamine and hydrazine substrates. It also has a role in the catabolism of the folate metabolite p-aminobenzoyl glutamate. Recent bioinformatics studies have correlated NAT1 expression with various cancer su...

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Detalhes bibliográficos
Main Authors: Tiang, Jacky M., Butcher, Neville J., Cullinane, Carleen, Humbert, Patrick O., Minchin, Rodney F.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3036737/
https://ncbi.nlm.nih.gov/pubmed/21347396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0017031
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