Glutathione S-transferase mu 1 (GSTM1) and theta 1 (GSTT1) genetic polymorphisms and atopic asthma in children from Southeastern Brazil

Xenobiotics can trigger degranulation of eosinophils and mast cells. In this process, the cells release several substances leading to bronchial hyperactivity, the main feature of atopic asthma (AA). GSTM1 and GSTT1 genes encode enzymes involved in the inactivation of these compounds. Both genes are...

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Detalhes bibliográficos
Main Authors: Lima, Carmen Silvia Passos, Néri, Iramaia Angélica, Lourenço, Gustavo Jacob, Faria, Isabel Cristina Jacinto, Ribeiro, José Dirceu, Bertuzzo, Carmen Silvia
Formato: Artigo
Idioma:Inglês
Publicado em: Sociedade Brasileira de Genética 2010
Assuntos:
Human and Medical Genetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3036117/
https://ncbi.nlm.nih.gov/pubmed/21637410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1590/S1415-47572010000300007
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