Glutathione S-transferase mu 1 (GSTM1) and theta 1 (GSTT1) genetic polymorphisms and atopic asthma in children from Southeastern Brazil

Xenobiotics can trigger degranulation of eosinophils and mast cells. In this process, the cells release several substances leading to bronchial hyperactivity, the main feature of atopic asthma (AA). GSTM1 and GSTT1 genes encode enzymes involved in the inactivation of these compounds. Both genes are...

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Bibliografiska uppgifter
Huvudupphovsmän: Lima, Carmen Silvia Passos, Néri, Iramaia Angélica, Lourenço, Gustavo Jacob, Faria, Isabel Cristina Jacinto, Ribeiro, José Dirceu, Bertuzzo, Carmen Silvia
Materialtyp: Artigo
Språk:Inglês
Publicerad: Sociedade Brasileira de Genética 2010
Ämnen:
Human and Medical Genetics
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3036117/
https://ncbi.nlm.nih.gov/pubmed/21637410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1590/S1415-47572010000300007
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