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Chromatin remodeling complex NURF regulates thymocyte maturation

The maturation of T cells requires signaling from both cytokine and T-cell receptors to gene targets in chromatin, but how chromatin architecture influences this process is largely unknown. Here we show that thymocyte maturation post-positive selection is dependent on the nucleosome remodeling facto...

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Autors principals: Landry, Joseph W., Banerjee, Subhadra, Taylor, Barbara, Aplan, Peter D., Singer, Alfred, Wu, Carl
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3034902/
https://ncbi.nlm.nih.gov/pubmed/21289071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.2007311
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