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Presynaptic Nicotinic α7 and Non-α7 Receptors Stimulate Endogenous GABA Release from Rat Hippocampal Synaptosomes through Two Mechanisms of Action

BACKGROUND: Although converging evidence has suggested that nicotinic acetylcholine receptors (nAChR) play a role in the modulation of GABA release in rat hippocampus, the specific involvement of different nAChR subtypes at presynaptic level is still a matter of debate. In the present work we invest...

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Main Authors: Zappettini, Stefania, Grilli, Massimo, Lagomarsino, Federica, Cavallero, Anna, Fedele, Ernesto, Marchi, Mario
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3034729/
https://ncbi.nlm.nih.gov/pubmed/21346795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0016911
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