Palmitoylethanolamide reduces granuloma-induced hyperalgesia by modulation of mast cell activation in rats

The aim of this study was to obtain evidences of a possible analgesic role for palmitoylethanolamide (PEA) in chronic granulomatous inflammation sustained by mast cell (MC) activation in rats at 96 hours. PEA (200-400-800 μg/mL), locally administered at time 0, reduced in a concentration-dependent m...

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Autors principals: De Filippis, Daniele, Luongo, Livio, Cipriano, Mariateresa, Palazzo, Enza, Cinelli, Maria Pia, de Novellis, Vito, Maione, Sabatino, Iuvone, Teresa
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2011
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3034677/
https://ncbi.nlm.nih.gov/pubmed/21219627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1744-8069-7-3
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