Two-dose-level confirmatory study of the pharmacokinetics and tolerability of everolimus in Chinese patients with advanced solid tumors

BACKGROUND: This phase I, randomized, multicenter, open-label study investigated the pharmacokinetics, safety, and efficacy of the oral mammalian target of rapamycin inhibitor everolimus in Chinese patients with advanced solid tumors. METHODS: A total of 24 patients with advanced breast cancer (n =...

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Autores principales: Xu, BingHe, Wu, YiLong, Shen, Lin, Ye, DingWei, Jappe, Annette, Cherfi, Azzeddine, Wang, Hui, Yuan, RuiRong
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2011
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Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3032760/
https://ncbi.nlm.nih.gov/pubmed/21232120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-8722-4-3
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