Optimization of glutathione production in batch and fed-batch cultures by the wild-type and recombinant strains of the methylotrophic yeast Hansenula polymorpha DL-1

BACKGROUND: Tripeptide glutathione (gamma-glutamyl-L-cysteinyl-glycine) is the most abundant non-protein thiol that protects cells from metabolic and oxidative stresses and is widely used as medicine, food additives and in cosmetic industry. The methylotrophic yeast Hansenula polymorpha is regarded...

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Библиографические подробности
Главные авторы: Ubiyvovk, Vira M, Ananin, Vladimir M, Malyshev, Alexander Y, Kang, Hyun Ah, Sibirny, Andriy A
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2011
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3032675/
https://ncbi.nlm.nih.gov/pubmed/21255454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6750-11-8
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