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A mouse dry eye model induced by topical administration of benzalkonium chloride

PURPOSE: To develop a dry eye model of mouse induced by topical administration of benzalkonium chloride (BAC) and investigate the possible mechanisms. METHODS: BAC at concentration of 0.2% was applied to the mouse ocular surface for 7 days. Phenol red thread tear test, tear break-up time (BUT) test,...

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Bibliographic Details
Main Authors: Lin, Zhirong, Liu, Xiaochen, Zhou, Tong, Wang, Yihui, Bai, Li, He, Hui, Liu, Zuguo
Format: Artigo
Language:Inglês
Published: Molecular Vision 2011
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3030605/
https://ncbi.nlm.nih.gov/pubmed/21283525
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