O-GlcNAcylation contributes to the vascular effects of ET-1 via activation of the RhoA/Rho-kinase pathway

AIMS: Glycosylation with β-N-acetylglucosamine (O-GlcNAcylation) is one of the most complex post-translational modifications. The cycling of O-GlcNAc is controlled by two enzymes: UDP-NAc transferase (OGT) and O-GlcNAcase (OGA). We recently reported that endothelin-1 (ET-1) augments vascular levels...

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Autors principals: Lima, Victor V., Giachini, Fernanda R., Carneiro, Fernando S., Carvalho, Maria Helena C., Fortes, Zuleica B., Webb, R. Clinton, Tostes, Rita C.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2011
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Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3028974/
https://ncbi.nlm.nih.gov/pubmed/20978008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvq338
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