Role of Defensins in Corneal Epithelial Barrier Function against Pseudomonas aeruginosa Traversal

Studies have shown that epithelium-expressed antimicrobial peptides (AMPs), e.g., β-defensins, play a role in clearing bacteria from mouse corneas already infected with Pseudomonas aeruginosa. Less is known about the role of AMPs in allowing the cornea to resist infection when healthy. We previously...

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Autori principali: Augustin, Danielle K., Heimer, Susan R., Tam, Connie, Li, Wing Y., Le Due, Jeff M., Evans, David J., Fleiszig, Suzanne M. J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2011
Soggetti:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3028852/
https://ncbi.nlm.nih.gov/pubmed/21115716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00854-10
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