Ablations of Ghrelin and Ghrelin Receptor Exhibit Differential Metabolic Phenotypes and Thermogenic Capacity during Aging

BACKGROUND: Obesity is a hallmark of aging in many Western societies, and is a precursor to numerous serious age-related diseases. Ghrelin (Ghrl), via its receptor (growth hormone secretagogue receptor, GHS-R), is shown to stimulate GH secretion and appetite. Surprisingly, our previous studies showe...

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Hauptverfasser: Ma, Xiaojun, Lin, Ligen, Qin, Guijun, Lu, Xinping, Fiorotto, Marta, Dixit, Vishwa D., Sun, Yuxiang
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2011
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3027652/
https://ncbi.nlm.nih.gov/pubmed/21298106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0016391
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