The effect of combined treatment with cisplatin and histone deacetylase inhibitors on HeLa cells

OBJECTIVE: To investigate the combined effects of cisplatin and the histone deacetylase (HDAC) inhibitors suberoylanilide hydroxamic acid (SAHA) or sirtinol on HeLa cells and assess the mechanism underlying HDAC inhibitor-cisplatin synergy. METHODS: The antineoplastic actions of cisplatin, SAHA and...

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Autors principals: Jin, Ke Long, Park, Jeong-Yeol, Noh, Eun Joo, Hoe, Kwang Lae, Lee, Joo Hak, Kim, Jong-Hyeok, Nam, Joo-Hyun
Format: Artigo
Idioma:Inglês
Publicat: Korean Society of Gynecologic Oncology and Colposcopy 2010
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3026306/
https://ncbi.nlm.nih.gov/pubmed/21278889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3802/jgo.2010.21.4.262
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