The Association of Genome-Wide Variation with the Risk of Incident Heart Failure in Adults of European and African Ancestry: A Prospective Meta-Analysis from the CHARGE Consortium

BACKGROUND: Although genetic factors contribute to the onset of heart failure (HF), no large-scale genome-wide investigation of HF risk has been published to date. We investigated the association of 2,478,304 single nucleotide polymorphisms (SNPs) with incident HF by meta-analyzing data from 4 commu...

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Główni autorzy: Smith, Nicholas L., Felix, Janine F., Morrison, Alanna C., Demissie, Serkalem, Glazer, Nicole L., Loehr, Laura R., Cupples, L. Adrienne, Dehghan, Abbas, Lumley, Thomas, Rosamond, Wayne D., Lieb, Wolfgang, Rivadeneira, Fernando, Bis, Joshua C., Folsom, Aaron R., Benjamin, Emelia, Aulchenko, Yurii S., Haritunians, Talin, Couper, David, Murabito, Joanne, Wang, Ying A., Stricker, Bruno H., Gottdiener, John S., Chang, Patricia P., Wang, Thomas J., Rice, Kenneth M., Hofman, Albert, Heckbert, Susan R., Fox, Ervin R., O’Donnell, Christopher J., Uitterlinden, Andre G., Rotter, Jerome I., Willerson, James T., Levy, Daniel, van Duijn, Cornelia M., Psaty, Bruce M., Witteman, Jacqueline C. M., Boerwinkle, Eric, Vasan, Ramachandran S.
Format: Artigo
Język:Inglês
Wydane: 2010
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Article
Dostęp online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3025695/
https://ncbi.nlm.nih.gov/pubmed/20445134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCGENETICS.109.895763
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