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Regulation of fat specific protein 27 by isoproterenol and TNF-α to control lipolysis in murine adipocytes

The lipid droplet-associated fat specific protein 27 (FSP27) suppresses lipolysis and thereby enhances triglyceride accumulation in adipocytes. We and others have recently found FSP27 to be a remarkably short-lived protein (half-life, 15 min) due to its rapid ubiquitination and proteasomal degradati...

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Hlavní autoři: Ranjit, Srijana, Boutet, Emilie, Gandhi, Pallavi, Prot, Matthieu, Tamori, Yoshikazu, Chawla, Anil, Greenberg, Andrew S., Puri, Vishwajeet, Czech, Michael P.
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Biochemistry and Molecular Biology 2011
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3023542/
https://ncbi.nlm.nih.gov/pubmed/21097823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M008771
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