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Galectin-3 preserves renal tubules and modulates extracellular matrix remodeling in progressive fibrosis

Renal tubular cell apoptosis is a critical detrimental event that leads to chronic kidney injury in association with renal fibrosis. The present study was designed to investigate the role of galectin-3 (Gal-3), an important regulator of multiple apoptotic pathways, in chronic kidney disease induced...

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Autori principali: Okamura, Daryl M., Pasichnyk, Katie, Lopez-Guisa, Jesus M., Collins, Sarah, Hsu, Daniel K., Liu, Fu-Tong, Eddy, Allison A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3023228/
https://ncbi.nlm.nih.gov/pubmed/20962111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00326.2010
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