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Phospholipid homeostasis regulates lipid metabolism and cardiac function through SREBP signaling in Drosophila

The epidemic of obesity and diabetes is causing an increased incidence of dyslipidemia-related heart failure. While the primary etiology of lipotoxic cardiomyopathy is an elevation of lipid levels resulting from an imbalance in energy availability and expenditure, increasing evidence suggests a rela...

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Autores principales: Lim, Hui-Ying, Wang, Weidong, Wessells, Robert J., Ocorr, Karen, Bodmer, Rolf
Formato: Artigo
Lenguaje:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3022264/
https://ncbi.nlm.nih.gov/pubmed/21245170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1992411
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