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Staphylococcus aureus ClpC Divergently Regulates Capsule via sae and codY in Strain Newman but Activates Capsule via codY in Strain UAMS-1 and in Strain Newman with Repaired saeS

ClpC is an ATPase chaperone found in most Gram-positive low-GC bacteria. It has been recently reported that ClpC affected virulence gene expression in Staphylococcus aureus. Here we report that ClpC regulates transcription of the cap operon and accumulation of capsule, a major virulence factor for S...

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Main Authors: Luong, Thanh T., Sau, Keya, Roux, Christelle, Sau, Subrata, Dunman, Paul M., Lee, Chia Y.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3021213/
https://ncbi.nlm.nih.gov/pubmed/21131496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00987-10
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