Beta-carotene affects gene expression in lungs of male and female Bcmo1(−/−) mice in opposite directions

Molecular mechanisms triggered by high dietary beta-carotene (BC) intake in lung are largely unknown. We performed microarray gene expression analysis on lung tissue of BC supplemented beta-carotene 15,15′-monooxygenase 1 knockout (Bcmo1 (−/−)) mice, which are—like humans—able to accumulate BC. Our...

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Main Authors: van Helden, Yvonne G. J., Godschalk, Roger W. L., Swarts, Hans J. M., Hollman, Peter C. H., van Schooten, Frederik J., Keijer, Jaap
Formato: Artigo
Idioma:Inglês
Publicado: SP Birkhäuser Verlag Basel 2010
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3021199/
https://ncbi.nlm.nih.gov/pubmed/20820853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-010-0461-0
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